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What side effects may I notice from taking Plaquenil?

Some people taking this medication over long periods of time or at high doses have developed irreversible damage to the retina of the eye. Stop taking Hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes.

Get emergency medical help if you have any of these signs of an allergic reaction to Hydroxychloroquine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

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